1. Instituto Nacional de Pediatría
2. INP
3. Tesis

Título :	Sindrome de Papillon-Lefevre Papillon-Lefevre Disease
Creador:	Jimenez Cordoba, Ileana
Nivel de acceso:	Open access
Palabras clave :	Enfermedad de Papillon - Lefevre Papillon-Lefevre Disease Papillon-Lefevre Papillon-Lefovre syndrume Palmar-plantar hyperkeratosis periodontal disease
Descripción :	The connection between palmar plantar hyperkeratosis and severe periodontal disease was first reported in 1924 by Papillon and Lefevre. Papillon-Lefevre syndrome (PLS) is described as the association of palmarplantar hyperkeratosis with precocious periodontal disease which results in exfoliation of primary and permanent dentitions. Periodontitis resulting from Papillon-Lefevre syndrome has been known to cause early loss of primary dentition with subsequent involvement of the permanent dentition. The 2 majar components of this syndrome (PLS) can also occur as distinct entities. The peripheral blood neutrophil chemotaxis and spontaneous migration were depressed in al/ patients with Papillon-Lefevre syndrome. The decreased chemotaxis of peripheral blood neutrophils strongly sugges"ts that the neutrophils may act as one of the important key determinants in the pathogenesis of severe periodontal destruction in patients with PLS. An increase in the CD29 lymphocytes and NK cells and a decrease in C045RA lymphocytes. These findings are important to explain 8 lymphocyte activation and the pathogenesis of the PLS. The combination of retinoid therapy and periodontal treatment improved the dermatologic and periodontal conditions.
Colaborador(es) u otros Autores:	Huerta López José G.
Fecha de publicación :	2000
Tipo de publicación:	Otros
Formato:	pdf
URI :	http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/798
Idioma:	spa
Aparece en las colecciones:	Tesis

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