Por favor, use este identificador para citar o enlazar este ítem:
http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/2812| Título : | Short report: limited and short-lasting humoral response in Taenia solium: seropositive households compared with patients with neurocysticercosis |
| Creador: | Meza Lucas A |
| Nivel de acceso: | Open access |
| Palabras clave : | Antígenos Helmínticos - inmunología Encefalopatías - epidemiología Encefalopatías - inmunología Neurocisticercosis - epidemiología Neurocisticercosis - inmunología Taenia - inmunología Antigens, Helminth - immunology Brain Diseases - epidemiology Brain Diseases - immunology Neurocysticercosis - epidemiology Neurocysticercosis - immunology Taenia - immunology |
| Descripción : | Epidemiologic data suggest that 30-40% of Taenia solium-seropositive people become spontaneously negative without acquiring cysticercosis. To compare the responses of these individuals with those of patients with neurocysticercosis, we screened seropositive persons among family members of 16 patients. We searched for specific antibodies in patients and their 118 households by an enzyme-linked immunoelectrotransfer blot assay using specific glycoproteins of T. solium metacestodes. We found six seropositive individuals without neurocysticercosis among members of four families. The matching patients were young, harbored viable cysts, and had short evolution of disease. The baseline response of healthy seropositive individuals was scarce and showed a low frequency of antibodies against glycoproteins GP39-42 and GP24, which are immunodominant in patients with neurocysticercosis. Moreover, they became spontaneously negative in few months. The response of patients was heterogeneous as shown in other studies. The results of this work support a highly dynamic host-parasite immunologic interaction and suggest individual susceptibility or level of exposure among family members |
| Colaborador(es) u otros Autores: | Carmona Miranda L García Jerónimo RC Torrero Miranda A González Hidalgo G López Castellanos G Correa D |
| Fecha de publicación : | 2003 |
| Tipo de publicación: | Artículo |
| Formato: | |
| Fuente: | Am J Trop Med Hyg 69(2):223-227 |
| URI : | http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/2812 |
| Idioma: | spa |
| Aparece en las colecciones: | Artículos |
Ficheros en este ítem:
No hay ficheros asociados a este ítem.
Los ítems de DSpace están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.