Relationship between sexual satiety and brain androgen receptors

Romano Torres, Mónica

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Título :	Relationship between sexual satiety and brain androgen receptors
Creador:	Romano Torres, Mónica
Nivel de acceso:	Open access
Palabras clave :	Análisis de varianza - ratas Andrógenos - sangre - ratas Encéfalo - anatomía & histología - ratas Encéfalo - metabolismo - ratas Ratas Wistar Receptores Androgénicos - metabolismo - ratas Respuesta de Saciedad - fisiología - ratas Factores Sexuales - ratas Conducta Sexual Animal - fisiología - ratas Analysis of Variance - rats Androgens - blood - rats Brain - anatomy & histology - rats Brain - metabolism - rats Rats, Wistar Receptors, Androgen - metabolism - rats Satiety Response - physiology - rats Sex Factors - rats Sexual Behavior, Animal - physiology - rats Sexual recovery after satiety Medial preoptic area Lateral septum Medial amygdala Ventromedial hypothalamic nucleus Androgen receptor immunocytochemistry
Descripción :	Recently we showed that 24 h after copulation to satiety, there is a reduction in androgen receptor density (ARd) in the medial preoptic area (MPOA) and in the ventromedial hypothalamic nucleus (VMH), but not in the bed nucleus of the stria terminalis (BST). The present study was designed to analyze whether the ARd changes in these and other brain areas, such as the medial amygdala (MeA) and lateral septum, ventral part (LSV), were associated with changes in sexual behavior following sexual satiety. Males rats were sacrificed 48 h, 72 h or 7 days after sexual satiety (4 h ad libitum copulation) to determine ARd by immunocytochemistry; additionally, testosterone serum levels were measured in independent groups sacrificed at the same intervals. In another experiment, males were tested for recovery of sexual behavior 48 h, 72 h or 7 days after sexual satiety. The results showed that 48 h after sexual satiety 30% of the males displayed a single ejaculation and the remaining 70% showed a complete inhibition of sexual behavior. This reduction in sexual behavior was accompanied by an ARd decrease exclusively in the MPOA-medial part (MPOM). Seventy-two hours after
Colaborador(es) u otros Autores:	Bryan V. Phillips-Farfán Roberto Chavira Gabriela Rodríguez-Manzo Alonso Fernández-Guasti
Fecha de publicación :	2007
Tipo de publicación:	Artículo
Formato:	pdf
Identificador del Recurso :	10.1159/000099250
Fuente:	Neuroendocrinology 85(1):16-26
URI :	http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/2762
Idioma:	eng
Aparece en las colecciones:	Artículos

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