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http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/2735| Título : | Prospective cohort study with active surveillance for fever in four dengue endemic countries in Latin America |
| Creador: | Dayan G |
| Nivel de acceso: | Open access |
| Palabras clave : | Adolescente Anticuerpos Antivirales - inmunología Antígenos Virales - sangre Brasil - epidemiología Niño Estudios de Cohortes Colombia -epidemiología Dengue - sangre Dengue - epidemiología Dengue - inmunología Virus del Dengue - inmunología Enfermedades Endémicas Monitoreo Epidemiológico Femenino Fiebre - epidemiología Fiebre - Inmunología Fiebre - virología Humanos Incidencia Masculino México - epidemiología Estudios Prospectivos Puerto Rico - epidemiología Adolescent Antibodies, Viral - immunology Antigens, Viral - blood Brazil - epidemiology Child Cohort Studies Colombia - epidemiology Dengue - blood Dengue - epidemiology Dengue - immunology Dengue Virus - immunology Endemic Diseases Epidemiological Monitoring Female Fever - epidemiology Fever - immunology Fever - virology Humans Incidence Male Mexico - epidemiology Prospective Studies Puerto Rico - epidemiology Dengue Virus del Dengue Enfermedades Endémicas Fiebre Estudios de Cohortes América Latina Dengue Dengue Virus Endemic Diseases Fever Cohort Studies Latin America |
| Descripción : | To prepare for a Phase III dengue vaccine efficacy trial, 20 investigational sites were selected for this observational study to identify dengue infections in a closed cohort (N = 3,000 children 9-16 years of age). Of 255 acute febrile episodes experienced by 235 children, 50 (21.3%) were considered serologically probable dengue, and 18 (7.7%) were considered virologically confirmed (i.e., dengue NS1 antigen positive) dengue cases. Considering the disease-free and at-risk period from study start to onset of symptoms, the overall incidence density of acute febrile episodes was 17.7 per 100 person-years of follow-up, ranging from 15.3 in Colombia to 22.0 in Puerto Rico. This study showed that all sites were capable of capturing and following up acute febrile episodes within a specific timeframe among the established cohort and to detect dengue cases. Copyright © 2015 by The American Society of Tropical Medicine and Hygiene. |
| Colaborador(es) u otros Autores: | Arredondo JL1 Carrasquilla G1 Deseda CC1 Dietze R1 Luz K1 Costa MS1 Cunha RV1 Rey LC1 Morales J1 Reynales H1 Miranda M1 Zambrano B1 Rivas E2 Garbes P1 Noriega |
| Fecha de publicación : | 2015 |
| Tipo de publicación: | Artículo |
| Formato: | |
| Identificador del Recurso : | 10.4269/ajtmh.13-0663 |
| Fuente: | American Journal of Tropical Medicine and Hygiene 93(1):18 - 23 |
| URI : | http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/2735 |
| Idioma: | eng |
| Aparece en las colecciones: | Artículos |
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