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http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/2605| Título : | Moieties in antidiabetic drugs as a target of insulin receptors in association with common neurological disorders (Review) |
| Creador: | Calderón Guzmán, David |
| Nivel de acceso: | Open access |
| Palabras clave : | Resistencia a la Insulina - fisiología Enfermedades Neurodegenerativas - metabolismo Insulina - metabolismo Insulina - uso terapéutico Obesidad - etiología Obesidad - metabolismo Obesidad - terapia Factores de Riesgo Obesidad - prevención & control Encéfalo - efectos de drogas Encéfalo - metabolismo Estrés Oxidativo Sistema Nervioso Central - metabolismo Enfermedad de Alzheimer - metabolismo Enfermedad de Parkinson - metabolismo Insulin Resistance - physiology Neurodegenerative Diseases - metabolism Insulin -metabolism Insulin -Therapeutic use Obesity - etiology Obesity - metabolism Obesity - therapy Risk Factors Obesity - prevention & control Brain - efectos de drogas Brain - metabolism Oxidative Stress Central Nervous System - metabolism Alzheimer Disease - metabolism Parkinson Disease - metabolism medicamentos antidiabéticos; sistema nervioso central; insulina; enfermedades neurodegenerativas; obesidad antidiabetic drugs; central nervous system; insulin; neurodegenerative disorders; obesity |
| Descripción : | Insulin is a peptide that can be harmful with regards to neuroplasticity, neuroprotection and neuromodulation. Furthermore, the role of insulin highlights its relevance in the progress of diverse clinical disorders as well as in the mechanisms associated with certain pathogenesis and their evolution towards diabetes, obesity and neurodegenerative diseases. The precise molecular mechanisms by which these diseases are induced remain to be elucidated. The benefits in knowing/discovering these mechanisms in animal models and humans cannot be undermined. An in depth understanding of the principal risk factors leading to obesity and their management is vital in the implementation of early-life strategies of intervention and prevention, with a view to avoid adverse late-life outcomes. Therefore, the aim of the present study was to review their possible association with antidiabetic drugs |
| Colaborador(es) u otros Autores: | Juárez-Olguín Mateo Hugo Hernández-García Ernestina Ortiz-Herrera N Osnaya Brizuela Norma |
| Fecha de publicación : | 2016 |
| Tipo de publicación: | Artículo |
| Formato: | |
| Identificador del Recurso : | 10.3892/br.2016.616 |
| Fuente: | Biomed Rep. 4(4):395-399 |
| URI : | http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/2605 |
| Idioma: | spa |
| Aparece en las colecciones: | Artículos |
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