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http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/2521| Título : | In vitro antimicrobial susceptibility in clinical isolates of Enterococcus species |
| Creador: | Calderón Jaimes E |
| Nivel de acceso: | Open access |
| Palabras clave : | Antibacterianos - farmacología Enterococcus - efectos de drogas Enterococcus - aislamiento y purificación Técnicas In Vitro Pruebas de Sensibilidad Microbiana - estadísticas y datos numéricos Anti-Bacterial Agents - pharmacology Enterococcus - drug effects Enterococcus - isolation & purification In Vitro Techniques Microbial Sensitivity Tests - statistics & numerical data resistencia microbiana a las drogas infecciones por enterobacteriaceae México drug resistance microbial enterobacteriaceae infections Mexico |
| Descripción : | Objective. To describe the antimicrobial activity of several antimicrobial agents against 97 clinical significant isolates of Enterococcus spp. Material and Methods. During a 2-year prospective study at Instituto Nacional de Pediatria (National Institute of Pediatrics) in Mexico City. Ninety seven strains of Enterococcus spp. (60 E. faecalis and 37 E. faecium) were tested against II antibiotics. Susceptibility tests were performed with agar, according to the standards of the sNational Committee for Clinical Laboratory Standards (NCCLS). Isolates were screened for high-level resistance (HLR) to β-lactams, aminoglycosides, glycopeptides and other antibiotics, as well as for vancomycin-phenotypes. Differences between proportions were evaluated with X2 of Fisher exact fest. Results. Overall resistance rates to the antibiotics tested were: 17/97 (17.5%) to penicillin, ampicillin, amoxicillin-clavulanate and imipenem. There was neither HLR nor β-lactamase production; 74/97 (48.4%) were resistant to erythromycin; 60% to ciprofloxacin; 31/97 (32%) to gentamicin, and 55/97 (56.7%) to streptomycin. Seven strains were vancomycin-resistant enterococci (VRE), all of them identified as E. faecium; 5/7 with Van A and 2/7 with Van B phenotypes. All the isolates were susceptible to linezolid. The difference in susceptibility among species was significant. Conclusions. Mutidrug-resistant enterococci is a real problem and continuous surveillance is necessary. The microbiology laboratory is the first line of defense against the spread of multiantibiotic-resistan enterococci in the hospital environment. All the strains recovered should be tested for susceptibility to ampicillin, streptomycin, gentamicin and glycopeptides. |
| Colaborador(es) u otros Autores: | Arredondo García JL Aguilar Ituarte F García Roca P |
| Fecha de publicación : | 2003 |
| Tipo de publicación: | Artículo |
| Formato: | |
| Fuente: | Salud Pública de México 45(2):96 - 101 |
| URI : | http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/2521 |
| Idioma: | eng |
| Aparece en las colecciones: | Artículos |
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