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http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/2488| Título : | Host gender in parasitic infections of mammals: an evaluation of the female host supremacy paradigm |
| Creador: | Morales Montor J |
| Nivel de acceso: | Open access |
| Palabras clave : | Cisticercosis - Inmunología, Cisticercosis - Metabolismo Sistema Endocrino - Fisiología Hormonas Esteroides Gonadales - Fisiologia Cysticercosis - Immunology Cysticercosis - metabolism Endocrine System - physiology Gonadal Steroid Hormones - physiology |
| Descripción : | A review of current literature on mammalian hosts' sexual dimorphism (SD) in parasitic infections revealed that (1) it is a scarcely and superficially studied biological phenomenon of considerable significance for individual health, behavior, and lifestyles and for the evolution of species; (2) there are many notable exceptions to the rule of a favorable female bias in susceptibility to infection; (3) a complex network of molecular and cellular reactions connecting the host's immuno-neuroendocrine systems with those of the parasite is responsible for the host-parasite relationship rather than just an adaptive immune response and sex hormones; (4) a lack of gender-specific immune profiles in response to different infections; (5) the direct effects of the host hormones on parasite physiology may significantly contribute to SD in parasitism; and (6) the need to enrich the reductionist approach to complex biological issues, like SD, with more penetrating approaches to the study of cause-effect relationships, i.e., network theory. The review concludes by advising against generalization regarding SD and parasitism and by pointing to some of the most promising lines of research. |
| Colaborador(es) u otros Autores: | Chavarria A De León MA Del Castillo LI Escobedo EG Sánchez EN Vargas JA Hernández Flores M RomoGonzález T Larralde C |
| Fecha de publicación : | 2004 |
| Tipo de publicación: | Artículo |
| Formato: | |
| Identificador del Recurso : | 10.1645/GE-113R3 |
| Fuente: | J Parasitol 90(3):531-546 |
| URI : | http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/2488 |
| Idioma: | eng |
| Aparece en las colecciones: | Artículos |
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