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http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/2397| Título : | Esophageal anastomotic failure: an experimental study |
| Creador: | Villegas Álvarez, Fernando |
| Nivel de acceso: | Open access |
| Palabras clave : | Anastomosis Quirúrgica - efectos adversos - Conejos Peso Corporal - Conejos Atresia Esofágica - cirugía - Conejos Esófago - anatomía & histología - Conejos Esófago - cirugía - Conejos Distribución Aleatoria - Conejos factores de riesgo - Conejos Dehiscencia de la Herida Operatoria - Conejos Tasa de Supervivencia - Conejos Suturas - Conejos Resistencia a la Tracción - Conejos Insuficiencia del Tratamiento - Conejos Anastomosis, Surgical -adverse effects - Rabbits Body Weight - Rabbits Esophageal Atresia - surgery - Rabbits Esophagus - anatomy & histology - Rabbits Esophagus - surgery - Rabbits Random Allocation - Rabbits Risk Factors - Rabbits Surgical Wound Dehiscence - Rabbits Survival Rate - Rabbits Sutures - Rabbits Tensile Strength - Rabbits Treatment Failure - Rabbits Atresia esofágica Complicaciones de anastomosis quirúrgicas Modo de animales quirúrgica Esophageal atresia Surgical anastomotic complications Surgical animal mode |
| Descripción : | Postsurgical complications in patients with esophageal atresia have remained unchanged during the last three decades. This study was aimed at investigating certain risk factors for small-sized esophageal anastomosis and to assess the probable relationship between esophageal length and body weight in rabbit. METHODS: Six groups of 10 adult rabbits were subjected to section or 1-cm segmental resection of thoracic esophagus followed by end-to-end anastomosis. Approximation strength of esophageal ends was measured. Three different suture materials were used, and three different surgeons carried out procedures. Observed morbidity was recorded, as well as leakage or stenosis frequency in suture line. Esophageal length and body weight of nonresected rabbits were measured. RESULTS: Fifteen leakages were observed in suture line; there were no differences in relative risk between groups with and without resection, or in ratio of this complication among surgeons; nonetheless, a greater number of leakages (p < 0.05) was observed at higher tension. There were no differences in magnitude of stenosis among surgeons, tension degree, or suture material used. Quadratic association was found between length of thoracic esophagus and body weight in nonresected rabbits. CONCLUSIONS: Rabbit esophagus is a suitable model to assess early surgical complications but not for late complications. Among three assessed factors, increased tension in patients with segmental deficit was the most significant factor in development of anastomotic leakage. Existence of nonlineal correlation between esophageal length and body weight in rabbit showed that resection of 1 cm of esophagus represented a different weight-dependent segmental deficit, which increased as weight decreased. |
| Colaborador(es) u otros Autores: | Olvera Duran J Rodríguez Aranda E Carmona Mancilla A Vigueras Villaseñor Rm Méndez Ramírez I. |
| Fecha de publicación : | 2003 |
| Tipo de publicación: | Artículo |
| Formato: | |
| Identificador del Recurso : | 10.1016/S0188-4409(03)00028-6 |
| Fuente: | Archives of Medical Research 34(3):171-175 |
| URI : | http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/2397 |
| Idioma: | eng |
| Aparece en las colecciones: | Artículos |
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