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http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/2394| Título : | Endocrine, neural and pharmacological aspects of sexual satiety in male rats |
| Creador: | Phillips Farfán BV |
| Nivel de acceso: | Open access |
| Palabras clave : | Antagonistas de Receptores Androgénicos - análisis - ratas Encéfalo - fisiología - ratas Dopamina - metabolismo - ratas Sistema Endocrino - fisiología - ratas Receptor alfa de Estrógeno - agonistas - ratas Receptor alfa de Estrógeno - antagonistas & inhibidores - ratas Receptor alfa de Estrógeno - metabolismo - ratas Neurotransmisores -farmacología - ratas Péptidos Opioides -metabolismo - ratas Proteínas Proto-Oncogénicas c-fos - metabolismo - ratas Conducta Sexual Animal - efectos de drogas - ratas Conducta Sexual Animal - fisiología - ratas Androgen Receptor Antagonists - analysis - rats Brain - physiology - rats Dopamine - metabolism - rats Endocrine System - physiology - rats Estrogen Receptor alpha - agonists - rats Estrogen Receptor alpha- antagonists & inhibitors - rats Estrogen Receptor alpha- metabolism - rats Neurotransmitter Agents - pharmacology - rats Opioid Peptides - metabolism - rats Proto-Oncogene Proteins c-fos - metabolism - rats Sexual Behavior, Animal - drug effects - rats Sexual Behavior, Animal - physiology - rats Saciedad sexual masculina de la rata, Receptor de andrógenos, Receptor de estrógenos alfa, c-Fos, Monoaminas, Opiáceos, GABA, Núcleo septal lateral, Amígdala medial, Área preóptica medial, Núcleo accumbens, Núcleo ventromedial del hipotálamo Male rat sexual satiety Androgen receptor Estrogen receptor alpha c-Fos Monoamines Opioids GABA Lateral septal nucleus Medial amygdala Medial preoptic area Nucleus accumbens Ventromedial nucleus of the hypothalamus |
| Descripción : | Sexual satiety is the inhibition of masculine mating behavior produced by copulation itself. This inhibition is manifested in different ways depending upon the species, the time and the amount of sexual behavior prior to sexual satiety. Pharmacological studies indicate that monoaminergic and opioidergic compounds modify this phenomenon in the rat and other species, possibly via a final dopaminergic pathway involving sexual motivation. Reduced androgen receptor expression and/or increased estrogen receptor alpha expression in specific brain areas are associated with the inhibition of mating behavior that characterizes rat sexual satiety. Androgen receptor over-expression in the same and other brain areas coincides with a partial recovery of rat male copulatory behavior after sexual satiety. The lateral septum, medial amygdala and medial preoptic area may participate in the neuroendocrine regulation of sexual satiety, based on changes in the expression of c-Fos, androgen receptor and estrogen receptor alpha in these cerebral regions. These data suggest that changes in steroid receptors, possibly triggered by modifications in neurotransmitters, underlie at least partly the inhibition of copulatory behavior characteristic of rat sexual satiety. © 2008 Elsevier Ltd. All rights reserved. |
| Colaborador(es) u otros Autores: | Fernández-Guasti A |
| Fecha de publicación : | 2009 |
| Tipo de publicación: | Revisión |
| Formato: | |
| Identificador del Recurso : | 10.1016/j.neubiorev.2008.11.003 |
| Fuente: | Neuroscience and Biobehavioral Reviews 33(3):442 - 455 |
| URI : | http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/2394 |
| Idioma: | eng |
| Aparece en las colecciones: | Artículos |
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