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Título : Cerebral malignant nerve sheath tumor, triton tumor variant: Case report
Creador: Calderón Garcidueñas, Lilian
Nivel de acceso: Open access
Palabras clave : CD57 antigen; desmin; MyoD1 protein; myoglobin; protein S 100; article; brain hemorrhage; brain tumor; case report; cell structure; clinical feature; computer assisted tomography; disease course; headache; histopathology; human; human tissue; immunohistochemistry; male; malignant neoplastic disease; nerve sheath tumor; occipital lobe; parietal lobe; postoperative period; preschool child; priority journal; protein expression; triton tumor; tumor localization; Brain Neoplasms; Child, Preschool; Fatal Outcome; Humans; Immunohistochemistry; Male; Nerve Sheath Neoplasms; Tomography, X-Ray Computed
Cerebral; Nerve sheath tumor; Triton tumor
Descripción : A case of a cerebral malignant triton tumor in a 3-year-old boy with a 2-month history of frontal headache and no clinical evidence of neurofibromatosis is reported. The computed tomography (CT) scan showed a large, irregular tumor in the right parietooccipital lobe. A partial surgical resection was performed. Histologically, the tumor was highly cellular and consisted of spindle cells with hyperchromatic and pleomorphic nuclei. Focally, neoplastic cells with rhabdomyoblastic features were found. The immunohistochemical study showed that tumor cells were positive for S-100 protein and CD57, and the rhabdomyoblasts expressed desmin, Myo-D1, and myoglobin. During the postoperative period, a massive intraparenchymal hemorrhage was identified and surgical drainage was performed. The patient worsened and died 10 days after the first surgery. Postmortem study was not authorized. Six cases of cerebral malignant nerve sheath tumor have been described; however, primary intraparenchymal malignant triton tumor has not been previously described.
Colaborador(es) u otros Autores: Bornstein-Quevedo L.
Peralta-Olvera F.
Marhx-Bracho A.
Rodríguez-Jurado R.
De Leon-bojorge B.
Fecha de publicación : 2003
Tipo de publicación: Artículo
Formato: pdf
Identificador del Recurso : 10.1007/s10024-001-0125-z
Fuente: Pediatric and Developmental Pathology 6(2):168 - 172
URI : http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/2088
Idioma: eng
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