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http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/1317| Título : | Infecciones nosocomiales por bacterias grampositivas multirresistentes: La actividad de nuevos antimicrobianos |
| Creador: | Morfín Otero Rayo |
| Nivel de acceso: | Open access |
| Palabras clave : | Infección Hospitalaria Bacterias Grampositivas Farmacorresistencia Bacteriana Múltiple Cross Infection Gram-Positive Bacteria Drug Resistance Multiple Bacterial Infecciones nosocomiales bacterias microbianas antimicrobianos. nosocomial infections pathogens antimicrobial. |
| Descripción : | Resistance in Gram-positive pathogens is a worldwide problem. The decrease of activity of available antibiotics has created a need for new antimicrobial agents. Linezolid is a member of the new class of antimicrobials, the oxazolidinones. Linezolid is active in vitro against staphylococci, streptococci, and Enterococci, including resistant strains such as methicillin-resistant S. aureus, penicillin-resistant Streptococcus pneumoniae, and vancomycinresistant Enterococci. Objective. To determine the in vitro activity of linezolid and other new antimicrobial active against gram-positive cocci. Material and methods. Two hundred and ninety six Grampositive cocci isolated from 4 different hospital in México in 2000 were analyzed. The susceptibility tests included a disk diffusion and the E test. Results. All S. aureus (Oxa-S), S. aureus (Oxa-R), Staphylococcus sp (Oxa-s) and Staphylococcus sp (Oxa-R) were susceptible to linezolid, quinupristin-dalfopristinn and vancomycin. Some Staphylococcus sp (Oxa-R) were resistant to teicoplanin (15%) and to clindamycin (54%). No vancomycin-resistant Enterococci were found. E. faecalis was frequently resistant to quinupristin-dalfopristin (89%). 50% of E. faecium were resistant to ampicillin. Resistance to penicillin in S. pneumoniae was 45%. Conclusions. Linezolid is a new potential treatment option for resistant gram-positive infections. |
| Colaborador(es) u otros Autores: | Donis Hernánadez José Arredondo José Luis Soriano Diana Hermida Carlos Heredia Cervantes Julia Esparza Ahumada Sergio Rodríguez Noriega Eduardo |
| Fecha de publicación : | 2002 |
| Tipo de publicación: | Artículo |
| Formato: | |
| Fuente: | Enf Infec y Micro 22(2):55-61 |
| URI : | http://repositorio.pediatria.gob.mx:8180/handle/20.500.12103/1317 |
| Idioma: | spa |
| Aparece en las colecciones: | Artículos |
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